Each cat will react to road trips differently, but it’s also understandable that sometimes cat parents don’t have a choice but to take their kitty on a long drive, either because they’re moving from one state or country to another.
The best way to make your cat’s stay in a carrier more tolerable, especially during a prolonged time, is by choosing a large-size carrier or crate with enough space to satisfy these basic needs.
If they have food, water, a litter box, and enough room in their carrier to stretch and stand upright, then a longer trip with appropriate breaks can be tolerable.